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Pancreatic carcinoma
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Pancreatic carcinoma

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Contributors: Peter Krasniak BS, Jennifer J. Findeis-Hosey MD
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Synopsis

Pancreatic carcinoma typically arises from the exocrine pancreas and is the fourth leading cause of cancer death in men and women in the United States. Ductal adenocarcinoma and its subtypes represent 85% of all pancreatic cancers, with the remainder due to mucinous cystic neoplasms, pancreatoblastoma, serous cystadenoma, and intraductal papillary-mucinous neoplasms. Pancreatic cancer is more common in men than women, and incidence increases with advancing age.

Risk factors for development of pancreatic cancer include a first-degree relative with exocrine pancreatic cancer, hereditary pancreatitis, nonhereditary chronic pancreatitis, and cigarette use.

Patients typically present with advanced disease, and signs and symptoms include pain, jaundice, and weight loss.

For more information, see OMIM.

Codes

ICD10CM:
C25.9 – Malignant neoplasm of pancreas, unspecified

SNOMEDCT:
372142002 – Carcinoma of pancreas

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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References

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Last Reviewed: 12/13/2017
Last Updated: 01/08/2018
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Pancreatic carcinoma
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Pancreatic carcinoma () : Abdominal pain, Diarrhea, Hepatomegaly, Jaundice, Nausea, Bilirubin elevated, Malaise, Trypsin elevated, Weight loss, Anorexia, Pruritus
Imaging Studies image of Pancreatic carcinoma
Axial non-contrast CT image demonstrates a relatively hyperattenuating mass within the body of the pancreas. Pathology was consistent with pancreatic neuroendocrine tumor.
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