Penile melanosis and lentiginosis - Anogenital in
Penile melanosis and lentiginosis may be seen in children and adults. When seen in children, it may be associated with Bannayan-Riley-Ruvalcaba syndrome, lentiginosis perigenito-axillaris syndrome, Carney complex, LEOPARD syndrome, Laugier-Hunziker syndrome, Dowling-Degos disease, or Peutz-Jeghers syndrome.
The pathogenesis of genital melanosis and lentiginosis is unknown. It is postulated that the hormonal influence on melanocytes could play a role. A history of cutaneous melanoma may be associated with an increased risk of genital melanosis and lentiginosis.
Penile melanosis and lentiginosis follows a benign course. Malignant transformation has not been reported. However, the diagnosis may be a marker of subsequent cutaneous melanoma development at other sites.
N48.89 – Other specified disorders of penis
239135006 – Genital lentiginosis
- Unlike penile lentiginoses, the lesions of erythrasma are found in the crural folds.
- Pigmented squamous cell carcinoma
- Pigmented Bowen disease
- Bowenoid papulosis
- Erythroplasia of Queyrat
- Pigmented condyloma
- Angiokeratomas of Fordyce
- Vascular tumor
- Seborrheic keratosis
- Pediculosis pubis
- Post-inflammatory hyperpigmentation
- Acanthosis nigricans
Last Updated: 07/21/2017