This summary addresses perioral dermatitis in children. Perioral dermatitis in adults is addressed separately.

Perioral dermatitis (also called periorificial dermatitis) is a benign inflammatory eruption characterized by erythematous papules and pustules around the mouth. The eruption may also involve periorbital and perinasal areas. Lesions are typically asymptomatic but may be mildly pruritic.

Childhood granulomatous periorificial dermatitis (CGPD) is an uncommon granulomatous variant of perioral dermatitis. CGPD predominantly affects prepubertal children and is thought to be more common among individuals with darker skin phototypes, although cases have been reported in individuals with lighter phototypes as well. CGPD may be mildly pruritic and may wax and wane for years.

Development of perioral dermatitis is often preceded by exposure to topical corticosteroids on the face. Inhaled and systemic corticosteroids have also been associated with perioral dermatitis. Various cosmetic products, including fluorinated toothpastes, have also been reported as potential precipitants of this condition.