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Periungual fibroma in Adult
See also in: Nail and Distal Digit
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Periungual fibroma in Adult

See also in: Nail and Distal Digit
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Contributors: Yoon-Soo Cindy Bae-Harboe MD, Noah Craft MD, PhD, Lowell A. Goldsmith MD, MPH
Other Resources UpToDate PubMed

Synopsis

Periungual fibromas are small, soft, and compressible lesions typically found in the lateral and posterior nail folds; in the context of tuberous sclerosis (TSC), they are also called Koenen tumors. They may be seen rarely in the general population (more commonly isolated, due to trauma) and are seen in 50% of patients with TSC (second-hit mutation allelic deletion of TSC2). Onset is typically in the second decade and as late as the fifth decade of life. No differences between sexes or among different ethnicities or races have been reported. Periungual fibromas are occasionally painful, and some are precipitated by trauma. They are more common on the toes than fingers.
 
Nontraumatic periungual fibromas are a major diagnostic criterion for the diagnosis of TSC. However, patients with a preceding history of trauma should also be examined for manifestations of TSC. "Red comets" (erythronychia) and longitudinal grooves may be found in nails of patients with TSC, and these findings should increase clinical suspicion of TSC, even in the absence of periungual fibromas.

Codes

ICD10CM:
D21.9 – Benign neoplasm of connective and other soft tissue, site unspecified

SNOMEDCT:
264561009 – Periungual fibroma

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Last Updated: 10/25/2018
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Periungual fibroma in Adult
See also in: Nail and Distal Digit
Print 13 Images
View all Images (13)
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Periungual fibroma : Fingernails, Nail fold tumor, Toenails
Clinical image of Periungual fibroma
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