Poikiloderma vasculare atrophicans - Skin
This condition is characterized by cutaneous findings of atrophic patches with telangiectasia and mottled pigmentation, usually on the trunk and flexural areas. The condition is typically asymptomatic; however, there may be pruritus and/or xerosis. Less often there may be tenderness in areas where fissuring or erosion/ulceration has occurred.
Onset is typically between 40 to 60 years of age, with a slight male predilection. Initial presentation may be with one to a few lesions that persist for many years. Over time the lesions may remain stable in size or gradually enlarge or thicken, as well as increase in number.
Progression to more advanced stages of mycosis fungoides or other cutaneous lymphomas is not reliably predictable, and the disease may remain quiescent for many years or indefinitely.
L94.5 – Poikiloderma vasculare atrophicans
16341002 – Poikiloderma vasculare atrophicans
- Chronic radiodermatitis
- Burns (see thermal or electrical burn; chemical burns are covered separately, by chemical agent)
- Dermatomyositis – poikilodermatous changes are usually in areas of chronic erythema; histiologic findings are consistent with connective tissue disease, eg, dermal mucin and interface changes.
- Acrodermatitis chronica atrophicans – a late stage of active infection with Borrelia afzelii. Affected areas may have dark-reddish discoloration; cryoglobulins are positive in the majority of patients.
- Localized scleroderma – presents with indurated lesions initially with progression to atrophy with a violaceous border.
- Lichen sclerosus – presents as ivory to porcelain-white colored plaques and papules with fissuring, telangiectasia, and sometimes erosion.
- Poikiloderma of Civatte – erythema with mottled hyperpigmentation, usually on the sun-exposed areas of the neck and upper chest.
- Genodermatoses including Rothmund-Thomson (poikiloderma congenitale) syndrome, Bloom syndrome (congenital telangiectatic erythema), dyskeratosis congenita, and xeroderma pigmentosum – usually will have other history and findings associated with syndrome.