Renal colic is the acute onset of severe abdominal / flank pain due to kidney stones. Pain typically radiates from the flanks to the groin and intensifies over the first 30-60 minutes. Eliciting a history of prior nephrolithiasis, a family history of kidney stones, or patients at risk of nephrolithiasis (eg, gastric bypass surgery, short bowel syndrome) should raise suspicion for a diagnosis of kidney stones. Some medications are associated with the development of kidney stones.
Physical examination often reveals an uncomfortable patient with difficulty finding a pain-free position and costovertebral angle tenderness. Many patients have associated nausea and/or vomiting, hematuria, or signs of infection. Atypical symptoms may include urinary frequency or urgency, difficulty urinating, or vague abdominal pain that may be mistaken for a urinary tract infection. Nephrolithiasis can occur at any age with a peak incidence between 20-49 years.
N23 – Unspecified renal colic
7093002 – Renal colic
Differential Diagnosis & Pitfalls
Drug Reaction Data
Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.