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Roseola - Skin
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Roseola - Skin

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Contributors: Craig N. Burkhart MD, Dean Morrell MD, Lowell A. Goldsmith MD, MPH, Nancy Esterly MD
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Synopsis

Roseola infantum (also known as sixth disease, exanthem subitum, and roseola infantum) is a mild self-limited illness that mainly affects children and is defined by its classic exanthem. HHV-6 and HHV-7 have been implicated as causal agents. Maternal antibodies are protective prior to the age of 6 months. Infants with roseola are typically between the age of 6 months and 1 year. The disease course classically begins with a high fever typically greater than 38.9 Celsius (102 Fahrenheit). The infant is otherwise well and the fever usually subsides on the fourth day.

The fever is followed immediately by the onset of asymptomatic rose-pink blanchable macules and papules 2-3 mm in diameter that begin on the trunk and may spread to the neck, upper and lower extremities. The rash typically lasts 1-2 days but can resolve more quickly.

Codes

ICD10CM:
B08.20 – Exanthema subitum [sixth disease], unspecified

SNOMEDCT:
54385001 – Sixth disease

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Last Updated: 08/22/2013
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Roseola - Skin
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Roseola : Erythema, Lymphadenopathy, Widespread, High fever, LYP increased, Blanching macules
Clinical image of Roseola
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