Sweet syndrome - Cellulitis
Sweet's syndrome may have extracutaneous manifestations. Symptoms such as fever, headaches, myalgias, malaise, and arthralgias are frequently present. Fever often precedes the appearance of lesions. The respiratory system is the most common organ system involved, with cough and infiltrates on chest X-ray, but other sites that may be affected include the GI tract, the musculoskeletal system, the kidneys, the heart, and the central nervous system. Conjunctivitis, episcleritis, and oral mucosal lesions have been reported. Sweet's syndrome often responds quite well to systemic corticosteroids, but recurrences are common.
Sweet's syndrome can be differentiated from cellulitis based on associated symptoms and the presence of numerous scattered lesions.
L98.2 – Febrile neutrophilic dermatosis [Sweet]
84625002 – Sweet's syndrome
- Sweet-like lesions have been seen at sites of erythropoietin injections. Lesions are sometimes mistaken for infiltration of the underlying hematologic malignancy.
- Pyoderma gangrenosum – Rolled border around purulent ulcers
- Neutrophilic eccrine hidradenitis
- Bowel-associated dermatosis – Arthritis syndrome
- Wells' syndrome
- Erythema multiforme – Targetoid lesions
- Drug eruption
- Urticarial vasculitis
- Erythema elevatum diutinum – Primarily over extensor surfaces
- Cutaneous small vessel vasculitis – Palpable purpura
- Behçet's disease – Associated with oral or genital ulcers
- Bromoderma or iododerma
- Bacterial infections (furunculosis, cellulitis)
- Mycobacterium marinum
- Erythema nodosum – Primarily over the shins
- Atypical mycobacterial infection
- Leishmaniasis (New World and Old World) – Recent travel to endemic areas
- Lymphoma / leukemia cutis
- Metastatic carcinoma