Signs of the sympathomimetic toxidrome include mydriasis, diaphoresis, hyperthermia, tachycardia, tremor, and hypertension. A patient may appear agitated. In extreme cases, seizures, rhabdomyolysis, or cardiac arrest may occur.
Treatment is usually supportive and includes cooling, hydration, antihypertensives, and benzodiazepines.
T44.904A – Poisoning by unspecified drugs primarily affecting the autonomic nervous system, undetermined, initial encounter
45536007 – Poisoning by sympathomimetic drug
- Alcohol withdrawal
- Cholinergic toxicity
- Anticholinergic toxicity
- Serotonin syndrome
- Drug side effects (eg, amphetamines [prescribed or recreational], ephedrine, salicylates)
- Psychiatric disorder
- Diabetic ketoacidosis
- Hyperthyroidism / thyrotoxicosis
- Electrolyte disturbance (eg, hypomagnesemia, hypophosphatemia)