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Emergency: requires immediate attention
Synthetic cannabinoid poisoning
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Emergency: requires immediate attention

Synthetic cannabinoid poisoning

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Other Resources UpToDate PubMed

Synopsis

Synthetic cannabinoids are a group of recreational drugs made with chemical compounds created in a laboratory to act on the same brain cell receptors as tetrahydrocannabinol (THC), the psychoactive ingredient in marijuana. These chemical compounds are different from THC, with distinct and unpredictable effects. This summary is a general discussion of synthetic cannabinoid poisoning. For information on serious bleeding and abnormal coagulation profiles associated with use of synthetic cannabinoids contaminated with brodifacoum, a long-lasting vitamin K antagonist used in rat poisoning, see Synthetic cannabinoid-associated coagulopathy.

Synthetic cannabinoids may be sprayed onto plant material and smoked, mixed into a liquid and vaped, or ingested. They are marketed under a variety of names including K2 and Spice. Synthetic cannabinoid products are sometimes sold in convenience stores as aromatherapy agents and may be labeled "not for human consumption." Many variations are now identified as Schedule I controlled substances in the United States, although new varieties continue to appear on the market. Manufacturers frequently alter the chemical composition of the products in an effort to circumvent existing state and federal laws.

Clinical features of synthetic cannabinoid poisoning vary and include neurologic, psychiatric, cardiovascular, and gastrointestinal symptoms as well as seizures, rhabdomyolysis, kidney failure, and death. Outbreaks have been identified by clusters of emergency department visits and poison center calls for illness due to synthetic cannabinoid use. Commonly reported adverse effects include tachycardia, tachypnea, increased blood pressure, vomiting, agitation, aggression / violent behavior, somnolence, and delirium / confusion.

Codes

ICD10CM:
T40.7X5A – Adverse effect of cannabis (derivatives), initial encounter

SNOMEDCT:
737335004 – Synthetic cannabinoid intoxication

Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated: 02/27/2019
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Emergency: requires immediate attention
Synthetic cannabinoid poisoning
Print 1 Images
Synthetic cannabinoid poisoning : Agitation, Altered mental state, Nausea, Vomiting, Anxiety, Tachycardia, Hypertension, Hallucination, synthetic cannabinoid
Copyright © 2019 VisualDx®. All rights reserved.