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Thrombophlebitis migrans
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Thrombophlebitis migrans

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Contributors: Paras Vakharia, Amor Khachemoune MD, Susan Burgin MD
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Synopsis

Recurrent superficial, or migratory, thrombophlebitis (also known as thrombophlebitis migrans or migratory thrombophlebitis, and Trousseau syndrome) usually presents as recurrent episodes of thrombophlebitis that occur simultaneously or successively in disparate locations of the subcutaneous fat over the trunk and lower extremities. Clinically, tender, erythematous cords or nodules are seen. Pathogenically, local thrombosis develops in superficial blood vessels due to a hypercoagulable state.

There is very high association with malignancies including carcinomas, such as adenocarcinomas of the pancreas and lung carcinomas. Armand Trousseau first reported this phenomenon in 1865 when he commented that unexpected thrombophlebitis could indicate an occult visceral malignancy.

These malignancies are often associated with the development of a hypercoagulable state. The exact mechanism for this is not fully elucidated. However, it is postulated that the tumors may secrete procoagulant factors, such as thromboplastin, that can lead to local clotting.

Related topic: Superficial Thrombophlebitis

Codes

ICD10CM:
I82.1 – Thrombophlebitis migrans

SNOMEDCT:
31268005 – Thrombophlebitis Migrans

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Last Reviewed: 12/06/2016
Last Updated: 12/06/2016
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Thrombophlebitis migrans
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Thrombophlebitis migrans : Erythema, Recurring episodes or relapses, Skin warm to touch, Tender skin lesion
Copyright © 2019 VisualDx®. All rights reserved.