Elongated and thicker eyelashes are frequently present in children with rare congenital syndromes such as Oliver-McFarlane syndrome and Cornelia de Lange syndrome.
Acquired disorders such as human immunodeficiency virus (HIV) infection, atopic dermatitis, allergic rhinitis, uveitis, and vernal keratoconjunctivitis may also be associated with trichomegaly.
Drugs that are commonly associated with eyelash growth are prostaglandin analogs, epidermal growth factor receptor inhibitors (EGFRIs), and MEK inhibitors, and less commonly interferon-alpha and cyclosporine.
L67.9 – Hair color and hair shaft abnormality, unspecified
279425004 – Disorder of hair
- Oliver-McFarlane syndrome – Congenital disorder associated with dwarfism, intellectual disability, and retina pigmentary degeneration.
- Cornelia de Lange syndrome – Congenital disorder associated with short stature; specific facial features; and cardiac, neurologic, gastrointestinal, and musculoskeletal malformations.
- HIV-infection-associated trichomegaly – Long and silky eyelashes (see HIV disease).
- Atopic-associated trichomegaly – Long and silky eyelashes (see atopic dermatitis).
- EGFRI and MEK inhibitor-associated trichomegaly – Coarse, curled, tortuous eyelashes.
- Prostaglandin analog-induced trichomegaly