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Viroptic toxicity - External and Internal Eye
See also in: Overview
Other Resources UpToDate PubMed

Viroptic toxicity - External and Internal Eye

See also in: Overview
Contributors: Brandon D. Ayres MD, Christopher Rapuano MD, Harvey A. Brown MD, Sunir J. Garg MD, Lauren Patty Daskivich MD, MSHS
Other Resources UpToDate PubMed

Synopsis

Toxic conjunctivitis due to topical medication use is a common problem. Toxicity can be secondary to the medication itself (as seen in Viroptic toxicity) or due to the preservative in multidose dropper vials. One of the more common preservatives used in ophthalmic preparations, benzalkonium chloride, is known to be toxic to the corneal epithelium. Toxic conjunctivitis is most common in patients using multiple topical medications. Patients will complain of red eyes, ocular irritation, tearing, and discharge. Symptoms can develop after a single use of the medication but typically do not begin until several weeks of usage have passed.

Codes

ICD10CM:
H10.219 – Acute toxic conjunctivitis, unspecified eye

SNOMEDCT:
415734002 – Toxic conjunctivitis due to drug

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated:02/17/2020
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Viroptic toxicity - External and Internal Eye
See also in: Overview
Viroptic toxicity : benzalkonium chloride, Bilateral distribution, Eye burning, Eye irritation, trifluridine, Conjunctival injection, Excessive tearing, Mucoid eye discharge
Clinical image of Viroptic toxicity
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