ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferencesView all Images (8)
Vulvar melanosis and lentiginosis - Anogenital in
Print
Other Resources UpToDate PubMed

Vulvar melanosis and lentiginosis - Anogenital in

Print Images (8)
Contributors: Vivian Wong MD, PhD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Genital melanosis and lentiginosis is a benign condition that is characterized by irregular pigmentation on the genital mucosa. Both females and males may be affected. In females, the vulvar mucosa is the most commonly involved site.

Vulvar melanosis and lentiginosis affects all age groups but favors perimenopausal women. When seen in children, it may be associated with Bannayan-Riley-Ruvalcaba syndrome, lentiginosis perigenito-axillaris syndrome, Carney complex, LEOPARD syndrome, Laugier-Hunziker syndrome, Dowling-Degos disease, or Peutz-Jeghers syndrome. Vulvar melanosis may also represent post-inflammatory hyperpigmentation from trauma, lichen sclerosus, or lichen planus.

The pathogenesis of genital melanosis and lentiginosis is unknown. It is postulated that hormonal influence on melanocytes could play a role. A history of cutaneous melanoma may be associated with an increased risk of genital melanosis and lentiginosis.

Vulvar melanosis and lentiginosis follows a benign course. Malignant transformation has not been reported. However, the diagnosis may be a marker of subsequent cutaneous melanoma development at other sites.

Codes

ICD10CM:
L81.4 – Other melanin hyperpigmentation

SNOMEDCT:
428876001 – Melanosis of vulva

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Reviewed: 05/23/2017
Last Updated: 07/21/2017
Copyright © 2019 VisualDx®. All rights reserved.
Vulvar melanosis and lentiginosis - Anogenital in
Print 8 Images
View all Images (8)
(with subscription)
Vulvar melanosis and lentiginosis : Brown color, Hyperpigmented macule, Irregular configuration, Labia majora, Labia minora/vestibule
Copyright © 2019 VisualDx®. All rights reserved.