Vulvar sebaceous adenitis (also known as genital neutrophilic sebaceous adenitis) is an extremely rare dermatosis of the vulva that is chronic and relapsing. It typically presents in premenopausal women in the fourth decade of life, although patients in their 20s and 40s have also been reported.

Vulvar sebaceous adenitis presents with one or more painful and tender yellowish-orange or erythematous papules on the labia minora. Some have been noted to discharge pus. The condition typically worsens in the luteal phase of the menstrual cycle and improves or resolves with the onset of menstruation. Cases that are menstrual cycle-independent have also been reported.

It is thought that cycle variation occurs as the sebaceous gland is under hormonal influence.

Related topic: Neutrophilic sebaceous adenitis