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Warty dyskeratoma
See also in: Hair and Scalp
Other Resources UpToDate PubMed

Warty dyskeratoma

See also in: Hair and Scalp
Contributors: Sujitha Yadlapati MD, Mari M. Batta DO, Belinda Tan MD, PhD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Warty dyskeratoma, or follicular dyskeratoma, is a relatively uncommon, benign, follicular adnexal neoplasm that usually appears between the fifth and seventh decades of life and is most prevalent in White men. The pathogenesis remains uncertain, but ultraviolet (UV) light, abnormal adhesion of keratinocytes, autoimmunity, and smoking may play a role. Architectural features resembling a wart-like growth have led to the suggestion of a viral infection to be the cause. However, human papillomavirus (HPV) infection has not been detected in these lesions.

Lesions usually present as a slow-growing, solitary, well-demarcated, skin-colored-to-red-brown umbilicated papule or nodule with a crusted, keratotic center. Most are asymptomatic; rarely, patients complain of pruritus or burning, and bleeding, crusting, or drainage may occur.

Warty dyskeratomas are most commonly located on sun-exposed areas of the body (scalp, face, and neck). They have been documented to coexist with other skin lesions, including actinic keratosis, squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and verruciform xanthoma. Multiple lesions, lesions involving the oral and vulvar mucosa, and subungual involvement have occasionally been reported. Eruptive warty dyskeratomas have been reported to occur in 2 patients with end-stage renal disease.

Warty dyskeratomas are benign. Malignant transformation has not been reported.

Codes

ICD10CM:
L85.8 – Other specified epidermal thickening

SNOMEDCT:
254676008 – Warty dyskeratoma

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Last Reviewed:02/02/2022
Last Updated:02/15/2022
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Warty dyskeratoma
See also in: Hair and Scalp
A medical illustration showing key findings of Warty dyskeratoma (Skin) : Face, Neck, Scalp, Umbilicated papule, Sun-exposed distribution
Clinical image of Warty dyskeratoma - imageId=5926976. Click to open in gallery.  caption: 'A large cluster of many discrete and confluent reddish papules, each with overlying thick scale, on the forearm.'
A large cluster of many discrete and confluent reddish papules, each with overlying thick scale, on the forearm.
Copyright © 2024 VisualDx®. All rights reserved.