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Xerosis in Adult
Other Resources UpToDate PubMed

Xerosis in Adult

Contributors: Nasir Aziz MD, Callyn Iwuala BA, Oyetewa Oyerinde MD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Xerosis (also called dry skin, asteatosis, or ashy skin) refers to a condition of rough, dry skin texture with associated fine scales. Xerosis is often pruritic. The pathogenesis involves a decrease in the amount of lipids in the stratum corneum and a deficiency in the water-binding capacity of this layer.

Xerosis is associated with a number of environmental factors and/or disease states, such as low humidity, frequent bathing, harsh soaps, ichthyoses, atopic dermatitis, hypothyroidism, Down syndrome, renal failure, malnutrition and malabsorptive states, human immunodeficiency virus disease, lymphoma, liver disease, Sjögren syndrome, carcinomatosis, and certain drugs.

The incidence of xerosis increases with age; nearly all individuals over the age of 60 have some degree of xerosis.

Codes

ICD10CM:
L85.3 – Xerosis cutis

SNOMEDCT:
89105000 – Xerosis cutis

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed:02/01/2021
Last Updated:01/31/2021
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Xerosis in Adult
Xerosis : Dry skin, Trunk, Pruritus, Fine scaly plaques, Legs, Dorsal hands
Clinical image of Xerosis
A close-up of diffuse scaling.
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