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Xerosis
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Xerosis

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Contributors: Kathryn Bowers MD, Pat Condry MD, Lowell A. Goldsmith MD, MPH
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Synopsis

Xerosis, also called dry skin or asteatosis, refers to a condition of rough, dry skin texture with fine scale and occasionally fine fissuring. In dark skin phototypes, xerosis causing "ashiness" reduces the skin's shine and presents as white patches called ashy skin xerosis. Xerosis is often pruritic. The pathogenesis involves a decrease in the amount of lipids in the stratum corneum and a deficiency in the water-binding capacity of this layer.

Xerosis is associated with a number of environmental factors and/or disease states, such as low humidity, frequent bathing, harsh soaps, ichthyoses, atopic dermatitis, hypothyroidism, Down syndrome, renal failure, malnutrition and malabsorptive states, human immunodeficiency virus disease, lymphoma, liver disease, Sjögren syndrome, carcinomatosis, and certain drugs.

The incidence of xerosis increases with age; nearly all individuals over the age of 60 have some degree of xerosis.

Codes

ICD10CM:
L85.3 – Xerosis cutis

SNOMEDCT:
89105000 – Xerosis cutis

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated: 08/09/2017
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Xerosis
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Xerosis : Dry skin, Fine scaly plaque, Leg, Trunk, Widespread, Pruritus
Clinical image of Xerosis
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