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Drug-induced paronychia - Nail and Distal Digit
Other Resources UpToDate PubMed

Drug-induced paronychia - Nail and Distal Digit

Contributors: Shari Lipner MD, PhD, Susan Burgin MD, Bertrand Richert MD, Robert Baran MD
Other Resources UpToDate PubMed

Synopsis

Paronychia is inflammation of the nail folds and may be either acute or chronic. Acute paronychia occurs rapidly and is associated with redness, pain, and, in the case of infection, purulent drainage. Chronic paronychia lasts for more than 6 weeks and is associated with erythema, loss of the cuticle, and often nail dystrophy.

Acute paronychia is generally due to infectious etiologies, while chronic paronychia is typically due to irritants. Medications are also responsible for some acute and chronic paronychias and correlate with the introduction of the drug. Reported drug culprits include retinoids, lamivudine, cyclosporine, indinavir, azidothymidine (AZT), cephalexin, sulfonamides, cetuximab, gefitinib, fluorouracil (5FU), methotrexate, vandetanib, capecitabine, doxorubicin, and docetaxel. The paronychia typically resolves once the medication is discontinued.

Codes

ICD10CM:
T50.995A – Adverse effect of other drugs, medicaments and biological substances, initial encounter

SNOMEDCT:
71906005 – Paronychia

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References

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Last Reviewed:07/20/2017
Last Updated:07/24/2017
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Drug-induced paronychia - Nail and Distal Digit
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A medical illustration showing key findings of Drug-induced paronychia : Nail fold erythema and edema, Nail pain, Periungual fingers
Clinical image of Drug-induced paronychia - imageId=2717438. Click to open in gallery.
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