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Inverse psoriasis in Adult
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Inverse psoriasis in Adult

Contributors: Jeffrey M. Cohen MD, Susan Burgin MD
Other Resources UpToDate PubMed


Inverse psoriasis, also known as intertriginous or flexural psoriasis, is a form of psoriasis that presents in skin folds such as the inframammary areas, the axillae, and the inguinal folds. The plaques of inverse psoriasis are morphologically similar to those of classic plaque psoriasis in that they are erythematous and sharply demarcated; however, inverse psoriasis lacks the thick silver scale, and instead has a surface that is smooth, moist, and sometimes macerated. Mechanical friction of opposing skin surfaces within flexural zones is thought to result in koebnerization (isomorphic response), which perpetuates the condition.

Inverse psoriasis affects up to 30% of patients who have plaque psoriasis, and it most commonly presents in the inguinal folds. The external genitalia is involved in up to 80% of individuals with inverse psoriasis.

Lesions may be pruritic, irritated, or painful. Inverse psoriasis is also associated with a decreased quality of life and may adversely impact intimate relationships.


L40.8 – Other psoriasis

238600001 – Flexural psoriasis

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Last Reviewed:07/25/2018
Last Updated:09/03/2018
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Inverse psoriasis in Adult
A medical illustration showing key findings of Inverse psoriasis : Erythema, Flexural distribution, Intertriginous distribution, Scaly plaque, Pruritus
Clinical image of Inverse psoriasis - imageId=14015. Click to open in gallery.  caption: 'Well-demarcated, salmon-pink papules with scant scale and a similar plaque in the axilla.'
Well-demarcated, salmon-pink papules with scant scale and a similar plaque in the axilla.
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