Dermatosis neglecta (DN) is a condition characterized by adherent scales that form due to inadequate cleaning or exfoliation of the skin. Whether due to deliberately poor or unwittingly neglectful personal hygiene, the lack of washing over the course of months allows for the accumulation of sebum, sweat, keratin, debris, bacteria, and yeast on unwashed areas of the skin. Pruritus may develop over the site, but there are no systemic symptoms. Washing with soap, water, and a washcloth for friction or with isopropyl alcohol-soaked gauze will often result in complete removal of the lesions.

DN may present in individuals with an underlying physical disability, hyperesthesia, previous trauma, or with a psychiatric etiology, resulting in areas of skin that remain persistently unwashed. Although not a life-threatening or contagious condition, it can be cosmetically bothersome.