Infantile anogenital digitate keratoses (IADK) is an idiopathic, benign condition that presents as digitate, keratotic projections in the anogenital area of infants. It is typically seen in the perianal area but may also more rarely be found in the genital skin, particularly in female infants.
IADK is more commonly reported in males than in females. It appears in the first few months of life, and lesions typically regress spontaneously within several months.
Infantile anogenital digitate keratoses
Alerts and Notices
Synopsis

Codes
ICD10CM:
L85.8 – Other specified epidermal thickening
SNOMEDCT:
238638002 – Multiple minute digitate hyperkeratosis of Goldstein
L85.8 – Other specified epidermal thickening
SNOMEDCT:
238638002 – Multiple minute digitate hyperkeratosis of Goldstein
Look For
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Staphylococcal folliculitis
- Candidiasis
- Condyloma acuminata
- Molluscum contagiosum
- Milia
- Infantile perianal pyramidal protrusions (IPPP)
- Irritant contact dermatitis
- Epidermal nevus
- Multiple minute digitate hyperkeratoses (MMDH) – presents in adults as nonfollicular papules on the trunk and extremities, sparing the anogenital region
- Papular acantholytic dyskeratosis – presents in adults as a papular eruption in the genital or inguinal areas
- Perianal pseudoverrucous papules and nodules – 2- to 15-mm, red, white, or gray, flat-topped papules or nodules, associated with encopresis or urinary incontinence
- Sexual abuse
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Management Pearls
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Therapy
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References
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Last Reviewed:07/15/2023
Last Updated:07/26/2023
Last Updated:07/26/2023