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Infantile anogenital digitate keratoses
Other Resources UpToDate PubMed

Infantile anogenital digitate keratoses

Contributors: Michael J. Woodbury BS, Susan Burgin MD
Other Resources UpToDate PubMed


Infantile anogenital digitate keratoses (IADK) is an idiopathic, benign condition that presents as digitate, keratotic projections in the anogenital area of infants. It is typically seen in the perianal area but may also more rarely be found in the genital skin, particularly in female infants.

IADK is more commonly reported in males than in females. It appears in the first few months of life, and lesions typically regress spontaneously within several months.


L85.8 – Other specified epidermal thickening

238638002 – Multiple minute digitate hyperkeratosis of Goldstein

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

  • Folliculitis
  • Candidiasis
  • Genital wart
  • Molluscum contagiosum
  • Milia
  • Infantile perianal pyramidal protrusion (IPPP)
  • Diaper irritant contact dermatitis
  • Keratinocytic epidermal nevus
  • Multiple minute digitate hyperkeratoses (MMDH) – presents in adults as nonfollicular papules on the trunk and extremities, sparing the anogenital region
  • Papular acantholytic dyskeratosis – presents in adults as a papular eruption in the genital or inguinal areas
  • Perianal pseudoverrucous papules and nodules – 2- to 15-mm, red, white, or gray, flat-topped papules or nodules, associated with encopresis or urinary incontinence
  • Child sexual abuse

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Management Pearls

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Last Reviewed:07/15/2023
Last Updated:07/26/2023
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Infantile anogenital digitate keratoses
A medical illustration showing key findings of Infantile anogenital digitate keratoses
Copyright © 2024 VisualDx®. All rights reserved.