Contents

SynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferences

View all Images (2)

Acquired Blaschko dermatitis
Other Resources UpToDate PubMed

Acquired Blaschko dermatitis

Contributors: Zachary Skabelund MD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Acquired Blaschko dermatitis (ABD; also known as blaschkitis, adult blaschkitis, or acquired relapsing self-healing Blaschko dermatitis) is a rare dermatologic disorder characterized by linear bands of papules or papulovesicles along Blaschko lines. These lines are thought to represent the embryologic migration of ectoderm, forming a V-shape over the spine, an arc or S-shape across the anterior and lateral torso, and straight lines down the upper and lower extremities. The etiology of the disease is thought to involve a T-cell mediated autoimmune reaction against genetically distinct keratinocytes in the context of genetic mosaicism.

The classic presentation of ABD involves a rapid onset of 1-4 mm pruritic, erythematous, edematous papules or papulovesicles that coalesce to form plaques across single or multiple lines of Blaschko. The bands are typically 2-4 cm wide, and when unilateral, there is a strict demarcation at the midline. Papules may have a fine scale. ABD typically resolves in weeks to months without treatment, though multiple recurrences may occur over the following months and years. The trunk is affected most frequently followed by the extremities, with rare involvement of the neck and face. The disease is typically seen among men and women in their fourth to fifth decade of life.

The classification of ABD has been controversial in the literature. Some authors classify it as the adult form of lichen striatus. Others view it as a separate diagnosis given its distinctive histopathology as well as the fact that typical lichen striatus cases are encountered in adults.

Codes

ICD10CM:
L30.9 – Dermatitis, unspecified

SNOMEDCT:
703938007 – Inflammatory dermatosis

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Updated:02/26/2020
Copyright © 2022 VisualDx®. All rights reserved.
Acquired Blaschko dermatitis
A medical illustration showing key findings of Acquired Blaschko dermatitis : Linear configuration, Primarily truncal distribution, Unilateral distribution, Pruritus, Smooth papules, Tiny papules
Copyright © 2022 VisualDx®. All rights reserved.