Contents

SynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferences

Information for Patients

View all Images (37)

Potentially life-threatening emergency
Acute meningococcemia in Child
Print Captions
Other Resources UpToDate PubMed
Potentially life-threatening emergency

Acute meningococcemia in Child

Print Patient Handout Images (37)
Contributors: Craig N. Burkhart MD, Dean Morrell MD
Other Resources UpToDate PubMed

Alerts and Notices

Synopsis

Acute meningococcemia : Altered mental state, Headache, Vomiting, Mottled configuration, Ecchymosis, Myalgia, Nuchal rigidity, High fever, WBC elevated
Meningococcal disease is a rapidly progressive infection caused by Neisseria meningitides, a gram-negative diplococcus bacterium. Infection begins as a nonspecific viral-like illness that rapidly evolves (within hours) into 1 of 2 main presentations: meningitis or septicemia. Most cases are acquired through exposure to asymptomatic carriers via respiratory droplets. Children aged younger than 5 years and teenagers aged 15-19 are predominantly affected.

Complications of acute meningococcemia include pericarditis / myocarditis, disseminated intravascular coagulation (DIC), meningitis and permanent neurologic sequelae, septic arthritis, osteomyelitis, adrenal hemorrhage (Waterhouse-Friderichsen syndrome), gangrene, and death.

Related topic: Chronic Meningococcemia

Codes

ICD10CM:
A39.2 – Acute meningococcemia

SNOMEDCT:
186365005 – Acute meningococcemia

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Multiple other diseases associated with vascular injury must be differentiated from meningococcal disease. Patients with congenital (clotting defects) or immune (vasculitis) causes of purpura and ecchymoses rarely have cardiovascular compromise. The large ecchymoses of meningococcal disease also tend to be well-defined, superficial, and have overlying necrosis, whereas large ecchymoses associated with clotting factor deficiencies or trauma are usually ill-defined, subcutaneous, and are not associated with necrosis. Nonspecific viral exanthems usually appear after a prodrome of several days, whereas patients with meningococcemia typically develop a rash in less than 24 hours of onset of an acute illness. Petechiae caused by coughing, crying, or vomiting are confined to the distribution of the superior vena cava (head, neck, and chest above the nipple line), whereas petechiae associated with meningococcemia are located over the entire torso and extremities.

Infection
Autoimmune Vasculitis
Toxin/Drug
Hematologic
Physical
  • Petechiae caused by coughing, vomiting, or crying
  • Trauma

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Updated:10/02/2019
Copyright © 2023 VisualDx®. All rights reserved.
Potentially life-threatening emergency
Acute meningococcemia in Child
Captions Print   Filter Images View all Images (37)
(with subscription) Reset
A medical illustration showing key findings of Acute meningococcemia : Altered mental state, Headache, Vomiting, Mottled configuration, Ecchymosis, Myalgia, Nuchal rigidity, High fever, WBC elevated
Clinical image of Acute meningococcemia - imageId=273564. Click to open in gallery. caption: 'Widespread petechiae and purpura, some with deep gunmetal gray centers (signifying necrosis), on the arm.'
Widespread petechiae and purpura, some with deep gunmetal gray centers (signifying necrosis), on the arm.

+35 More images of Acute meningococcemia with subscription

Copyright © 2023 VisualDx®. All rights reserved.