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Alopecia areata in Infant/Neonate
See also in: External and Internal Eye,Hair and Scalp,Nail and Distal Digit
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Alopecia areata in Infant/Neonate

See also in: External and Internal Eye,Hair and Scalp,Nail and Distal Digit
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Contributors: Vivian Wong MD, PhD, Sarah N. Robinson MD, Mary Gail Mercurio MD, Belinda Tan MD, PhD, Susan Burgin MD
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Synopsis

Alopecia areata : Sparse eyebrows, Eyelash loss, Round areas of alopecia, Eyebrows
Alopecia areata is a T-lymphocyte mediated autoimmune disease of the hair follicle resulting in nonscarring hair loss. Most cases are limited to 1 or 2 small patches of alopecia that involve the scalp, eyebrows, or body hair, but in severe cases, all hair on the scalp is lost (alopecia totalis) or all scalp and body hair is lost (alopecia universalis). History of sudden onset is characteristic.

Alopecia areata is seen equally in both sexes and in patients of all ages and ethnicities; however, it is most commonly seen in patients between the ages of 5 and 40. There is an increased incidence of alopecia areata in patients with Down syndrome as well as those with autoimmune diseases, most commonly thyroid disease. In addition, there may be a family history of alopecia areata or autoimmune disease. Patients with alopecia areata are also more likely to have atopy, and its presence is felt to be a poor prognostic indicator.

The course of alopecia areata is unpredictable, with wide variation in duration and extent of disease occurring from patient to patient. In most patients, hair will eventually spontaneously regrow, although recurrences are common. The condition is treatable but cannot be cured.

Codes

ICD10CM:
L63.9 – Alopecia areata, unspecified

SNOMEDCT:
68225006 – Alopecia areata

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

  • Trichotillomania, from the twisting and pulling of hair, may mimic alopecia areata. Hairs are broken off at varying lengths.
  • Telogen effluvium, usually secondary to recent major illness, surgery, or malnutrition. The loss is diffuse, not localized.
  • Tinea capitis, usually associated with scale, active inflammation, lymphadenopathy, and pruritus.
  • Loose anagen syndrome may have short, thin hair that can easily be removed from the scalp with gentle pulling, typically seen in young children.

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed:06/28/2022
Last Updated:06/30/2022
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Alopecia areata in Infant/Neonate
See also in: External and Internal Eye,Hair and Scalp,Nail and Distal Digit
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A medical illustration showing key findings of Alopecia areata : Sparse eyebrows, Eyelash loss, Round areas of alopecia, Eyebrows
Clinical image of Alopecia areata - imageId=3997565. Click to open in gallery. caption: 'A smooth round patch of nonscarring alopecia on the occipital scalp with early hair regrowth after intralesional steroid injection.'
A smooth round patch of nonscarring alopecia on the occipital scalp with early hair regrowth after intralesional steroid injection.

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