Anetoderma in Adult
Anetoderma may be primary or secondary. Primary anetoderma occurs when there is no underlying skin disorder. Cardiac, ocular, bony, and other abnormalities have been reported to occur in some patients with primary anetoderma.
The lesions of secondary anetoderma are identical to those of primary anetoderma but appear at the same sites as a preceding dermatosis. A multitude of conditions are associated with the development of secondary anetoderma. These include varicella, folliculitis, acne vulgaris, lichen planus, syphilis, granuloma annulare, tuberculosis, human immunodeficiency virus (HIV), pyoderma gangrenosum, Steven-Johnson syndrome, B-cell lymphoma, juvenile xanthogranuloma, melanocytic nevi, sarcoidosis, dermatofibromas, prurigo nodularis, lupus erythematosus, leprosy, mastocytosis, plasmacytomas, xanthomas, lymphocytoma cutis, acrodermatitis chronica atrophicans, pilomatricoma, antiphospholipid antibody syndrome, penicillamine, nodular amyloidosis, and hepatitis B immunization. The development of punctate anetoderma has been reported in patients receiving nivolumab and cabiralizumab with stereotactic body radiotherapy.
Anetoderma has also been described in premature neonates (see Anetoderma of prematurity). Rare reports of familial anetoderma have also been documented.
L90.1 – Anetoderma of Schweninger-Buzzi
L90.2 – Anetoderma of Jadassohn-Pellizzari
238828009 – Anetoderma
Differential Diagnosis & Pitfalls
- Atrophia maculosa varioliformis cutis and atrophoderma vermiculatum are limited to the face.
- Connective tissue nevi
- Mid-dermal elastolysis
- Cutis laxa
- Focal dermal hypoplasia syndrome
- Nevus lipomatosus superficialis of Hoffman and Zurhelle
- Atrophoderma of Pasini and Pierini
- Pseudoxanthoma elasticum
- Insect bites (early lesions)
- Papular urticaria (early lesions)
Drug Reaction Data