ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyDrug Reaction DataReferencesView all Images (10)
Angiolipoma
Other Resources UpToDate PubMed

Angiolipoma

Contributors: Rajini Murthy MD, Belinda Tan MD, PhD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Angiolipomas are benign soft tissue tumors composed of adipocytes. Clinically, they resemble lipomas, but they may be slightly firmer on palpation. While lipomas are typically asymptomatic, angiolipomas can be tender or painful. Angiolipomas differ from lipomas in their composition because they include vascular and neural elements. Angiolipomas are usually less than 2 cm in size and may be solitary or multiple. They are most commonly found on the forearms, but they may also occur on the trunk or upper arms. Approximately 5% of angiolipomas are familial, most often following an autosomal recessive transmission pattern.

Symptomatic angiolipomas have been noted to appear with the initiation of antiretroviral therapy in HIV patients. This may be associated with fat redistribution that has been observed with protease inhibitors.

Extracutaneous angiolipomas may also occur. They may be found in the kidneys in association with tuberous sclerosis. They account for less than 1% of spinal tumors, in which case they may be associated with spina bifida.

Codes

ICD10CM:
D17.9 – Benign lipomatous neoplasm, unspecified

SNOMEDCT:
404057003 – Angiolipoma

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Lipomas usually are not tender or painful.
  • Epidermoid cysts (epidermal inclusion cysts) have a characteristic overlying punctum.
Differential diagnosis of painful benign tumors:

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

Subscription Required

References

Subscription Required

Last Reviewed:01/18/2021
Last Updated:01/25/2021
Copyright © 2021 VisualDx®. All rights reserved.
Angiolipoma
Angiolipoma : Forearm, Trunk, Painful skin lesion
Clinical image of Angiolipoma
Copyright © 2021 VisualDx®. All rights reserved.