Contents

SynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyDrug Reaction DataReferences

View all Images (6)

Baboon syndrome
Other Resources UpToDate PubMed

Baboon syndrome

Contributors: Vivian Wong MD, PhD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Baboon syndrome refers to a pattern of cutaneous eruption with predominant involvement of the buttocks resembling the hairless, red buttocks of baboons. The upper inner thighs and at least one flexural site are often affected. Baboon syndrome may be seen in symmetric drug-related intertriginous and flexural exanthema (SDRIFE) or systemic contact dermatitis (SCD), although nomenclature remains a challenge; the relationship between baboon syndrome, SDRIFE, and SCD is still being evaluated.

SDRIFE is a type of drug eruption favoring the intertriginous and flexural skin following systemic exposure to medication, most commonly antibiotics. SCD occurs when systemic exposure to a hapten triggers a generalized contact-type allergic dermatitis. Triggers may include drugs, metals, foods, plants, and medical implants. In both conditions, the eruption could present as baboon syndrome. T cell-mediated delayed type hypersensitivity reaction may contribute to both disease processes. Both conditions carry a benign disease course, with resolution upon discontinuation of allergen exposure.

Codes

ICD10CM:
L25.8 – Unspecified contact dermatitis due to other agents

SNOMEDCT:
277804000 – Baboon Syndrome

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

To perform a comparison, select diagnoses from the classic differential

Subscription Required

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

Drug Reaction Data

Subscription Required

References

Subscription Required

Last Reviewed:04/17/2017
Last Updated:01/22/2019
Copyright © 2024 VisualDx®. All rights reserved.
Baboon syndrome
A medical illustration showing key findings of Baboon syndrome : Bilateral distribution, Buttocks, Confluent configuration, Erythema, Genitals, buttocks, perineum, Intertriginous distribution
Clinical image of Baboon syndrome - imageId=1052237. Click to open in gallery.  caption: 'Bright red plaques on the buttocks.'
Bright red plaques on the buttocks.
Copyright © 2024 VisualDx®. All rights reserved.