Beau lines - Nail and Distal Digit
Beau lines can be caused by trauma or local disease involving the nail fold, such as manicuring or paronychia, respectively. They may also result from metabolic or inflammatory influences, both local and systemic. When Beau lines are present in all nails at a similar location on the nail plate, there is likely to be a systemic cause, such as myocardial infarction, pemphigus vulgaris, Raynaud phenomenon, or rheumatic fever. As a drug effect, they are most commonly seen with chemotherapeutic agents. In immunosuppressed patients, they may be due to decreased nutrition from gastrointestinal disease or drugs.
In children, hand-foot-and-mouth-disease is a common cause of Beau lines.
Onychomadesis is a complete halt in nail plate production and is a severe form of Beau lines.
L60.4 – Beau's lines
44087005 – Beau's lines
Differential Diagnosis & Pitfalls
- Muehrcke lines – Paired white transverse bands resulting from hypoalbuminemia, liver disease, malnutrition, chemotherapy, or human immunodeficiency virus (HIV) infection.
- – Parallel transverse grooves.
- Mees' lines – Transverse white bands resulting from arsenic poisoning, infections, systemic lupus erythematosus, acute renal failure, heart failure, chemotherapy, or ulcerative colitis.
- – White band proximally and a red-brown band distally, resulting from chronic renal disease, Kawasaki disease, liver and gastrointestinal diseases, zinc deficiency, and chemotherapy.
- – A white band involving more than 80% of the total nail length, resulting from hepatic cirrhosis, heart failure, diabetes mellitus, and infections.
Drug Reaction Data