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Bedbug bite in Adult
Other Resources UpToDate PubMed

Bedbug bite in Adult

Contributors: Susan Burgin MD, Whitney A. High MD, JD, MEng
Other Resources UpToDate PubMed


Bedbugs (Cimex lectularis) are 4-5 mm ovoid, flat, wingless, red-brown, nocturnal, blood-sucking insects. The insects hide during the day in the seams of mattresses, in the crevices of box springs, and in the cracks of floors and walls. Bedbugs require a blood meal to progress in their life cycle. The insects feed weekly and prefer to bite in the predawn hours. While a blood meal is required to advance in the life cycle, bedbugs have been known to survive up to 12 months without a blood meal. In the absence of a human host, bedbugs may feed on other animals. The bedbug can travel by concealing itself or its eggs within the dark recesses of suitcases and other personal effects, including clothing.

Bedbugs have afflicted humans for thousands of years but became uncommon after World War II because of widespread use of modern insecticides. Beginning in 1995, a resurgence in bedbug infestations was noted, with rates almost doubling annually in North America, Western Europe, and Australia.

Increased national and international tourism, changes in pesticide use (including a prohibition on DDT), and use of recycled mattresses are thought to contribute to this epidemic of bedbug activity. Contrary to popular belief, cleanliness and hygiene have little impact on bedbug infestation. The insects are attracted to humans based on temperature and carbon dioxide production. Bedbugs are most prevalent in urban areas, likely due to population density and/or crowding.

At present, it is not believed that bedbugs are important vectors of disease transmission, such as human immunodeficiency virus (HIV) or hepatitis B or C. Patients with bedbug bites often come to medical attention seeking relief of resultant pruritus and skin lesions.


W57.XXXA – Bitten or stung by nonvenomous insect and other nonvenomous arthropods, initial encounter

242649000 – Bite of bed bug

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Last Reviewed:05/04/2017
Last Updated:07/01/2020
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Patient Information for Bedbug bite in Adult
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Bedbugs are small wingless insects (Cimex lectularius) that come out at night to feed. They live in dry, dark crevices such as the seams of mattresses, furniture, floorboards, wallpaper, and suitcases. Their only food source is blood, and they can live for up to a year without a meal. Their bite is painless, so you will likely not be awoken. They usually feed in the very early morning hours, which explains why they are mostly found in and around your bed. It can take up to 30 minutes for them to complete their meal. In the absence of the bedbug's preferred human host, it will feed on any warm-blooded mammal.

Who’s At Risk

Bedbugs do not discriminate, so anyone can be affected. Additionally, there is usually no relationship between a bedbug infestation and poor hygiene or an unclean home. They are most commonly found in places where there are a high number of people, such as in hotels, prisons, shelters, apartment buildings, and dorms. They can travel to your home in used furniture or in suitcases.

Bedbug infestations have been on the rise. This is thought to be due to recent increases in international travel along with changes in insect pesticides that do not affect the bedbug but do kill the bedbug's natural predators, the cockroach and red ant.

Signs & Symptoms

The morning after being bitten the bedbug, you may notice an itchy hive-like bump at the site of the bite mark, which will go away through the course of the day. There may or not may not be a visible bite mark in the center of the bump. After that, what start as small bruise-like areas turn into red, intensely itchy bumps on the exposed parts of the body (arms, legs, chest, and sometimes the face). There may be a clustered configuration of 3 bites in a line (commonly known as "breakfast, lunch, and dinner"). Resolution takes about 2 weeks and leaves some darkening of the skin (post-inflammatory hyperpigmentation).

You may see tell-tale signs of the bedbug's presence, such as blood stains on the sheets, flecks of bedbug dung on or around your bed, or you may smell a sweet odor that occurs when there is a large bedbug infestation. You may be able to spot a moving bedbug if you are searching at night.

Self-Care Guidelines

The management of bedbug bites includes removing the bedbug infestation and controlling the itching.

The best time to look for live bedbugs is the middle of the night, when they come out to feed. Wash all linens in hot water and dry in a hot dryer. You may also need to wash your curtains. Scrub furniture to remove eggs, and fix any cracks that may be in the furniture; you may need to take the furniture apart to do this well. Vacuum the room, including the mattress (concentrating on the seams) and any surrounding crevices. You may want to fill and seal any cracks around the room and paste down any rolling wallpaper seams. Check the adjoining rooms for bugs as well, even if the occupants don't complain of itching.

Sometimes, in cases of severe infestation, it may be best to have a licensed pest control agent inspect and eradicate the bedbugs. Be aware that some insect repellants can be toxic to children, so make sure to find out exactly what chemicals they will be using and what the chemical's risk profile is.

Benadryl (diphenhydramine) can be used to control the itching. A low-strength topical corticosteroid cream or ointment, such as hydrocortisone, can be purchased over the counter to help with itching.

When you travel and stay in hotels, keep your suitcase and clothing away from the bed or other furniture. Upon returning home, wash the clothing you took with you, and place your suitcase in an attic, basement, or garage, where there is little chance of the bugs encountering humans for prolonged periods at night.

When to Seek Medical Care

Bedbugs can create considerable anxiety. You may need a prescription-strength topical steroid to help intensely itchy bites. Scratching the bite sites may cause infection, so if there is pus, redness, swelling, fever, or the reactions blister or are otherwise severe, you should see your doctor. There have been rare cases of severe allergic reaction that affects breathing (anaphylaxis), which requires immediate emergency medical care.


Your doctor may give you an antihistamine, such as Benadryl, and/or topical corticosteroids to help reduce the itching and inflammation. In rare cases of blistering skin reaction, oral corticosteroids may be necessary. If you have a bacterial infection of the skin from scratching, you may need oral antibiotics. Rarely, anaphylaxis has occurred and is treated with emergency care.

Bedbug bites are difficult to visually diagnose, so if you continue to get lesions, your doctor may need to take a small sample of skin (biopsy) to determine if you have some other skin condition.


Ter Poorten, M, et al. The Return of the Common Bedbug. Pediatric Dermatology 22 (3), 183-187, 2005 May.
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Bedbug bite in Adult
A medical illustration showing key findings of Bedbug bite : Grouped configuration, Trunk, Blanching macule, Pruritus, Insect bite, Round shape
Clinical image of Bedbug bite - imageId=3133638. Click to open in gallery.  caption: 'Urticarial papules on the arm.'
Urticarial papules on the arm.
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