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Benign prostatic hyperplasia
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Benign prostatic hyperplasia

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Contributors: Amirah Khan MD, Pamela L. Sloan MD, Paritosh Prasad MD
Other Resources UpToDate PubMed

Synopsis

Benign prostatic hypertrophy (BPH) is a noncancerous enlargement of the prostate gland due to hypertrophic glands, causing blockage of urine flow. This disorder is common in men over 50, tends to be slowly progressing, and leads to significant disability. It is characterized by urinary dysfunction (frequency, urgency, nocturia, incomplete emptying, and incontinence) and disruption in urinary stream (hesitancy, intermittent flow, dribbling of urine). This spectrum of symptoms is categorized as lower urinary tract symptoms (LUTS). Severity of symptoms can be determined by use of the American Urological Association Symptom Index, which can help guide management. Potential risk factors for the development of BPH include elevated protein-specific antigen (PSA) and obesity. BPH is not a known risk factor for prostate cancer.

Management includes modifications in routine (limiting fluids at bedtime, caffeine intake, and diuretics) and medications. BPH can cause acute urinary retention, which requires catheterization. Patients with poor results may seek surgical treatment such as transurethral resection of the prostate, transurethral incision of the prostate, or prostate laser surgery.

Codes

ICD10CM:
N40.0 – Enlarged prostate without lower urinary tract symptoms

SNOMEDCT:
266569009 – Benign Prostatic Hyperplasia

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed: 01/04/2019
Last Updated: 01/15/2019
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Benign prostatic hyperplasia
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Benign prostatic hyperplasia : Urinary frequency, Urinary incontinence, Urinary retention, Nocturia, Urinary urgency
Imaging Studies image of Benign prostatic hyperplasia
Axial CT image demonstrates enlarged prostate in this patient with known BPH.
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