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Bowenoid papulosis - Anogenital in
See also in: Immunocompromised, HIV and AIDS
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Bowenoid papulosis - Anogenital in

See also in: Immunocompromised, HIV and AIDS
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Contributors: Mary Spencer MD, Ann Lenane MD, Sireesha Reddy MD, Amy Swerdlin MD, Manasi Kadam Ladrigan MD, Carol Berkowitz MD
Other Resources UpToDate PubMed

Synopsis

Bowenoid papulosis is a persistent HPV-associated dermatosis that is sexually transmitted and differs from genital warts by histology. Microscopically, bowenoid papulosis resembles squamous cell carcinoma (SCC) in situ. Bowenoid papulosis has been associated with cervical intraepithelial neoplasia and rarely with squamous cell carcinoma in adults. Occasionally it is self-remitting.

The disorder is most common in young, sexually active adults. However, childhood cases have been reported. Papules are induced virally by the human papillomavirus, with type 16 present in an overwhelming majority of cases. Lesions occur most commonly on the shaft of the penis, although they can occur anywhere on the genitalia and in the perianal region. Bowenoid papulosis typically presents as solitary or multiple small, pigmented (red, brown, or flesh-colored) papules with a flat to verrucous surface. The lesions can coalesce into larger plaques.

Although evidence of pediatric bowenoid papulosis does not confirm sexual abuse, the possibility of sexual transmission should be investigated. Childhood sexual abuse is a problem of epidemic proportions affecting children of all ages and economic and cultural backgrounds. Although awareness is increasing, it is often challenging to differentiate findings attributable to child abuse from those of bowenoid papulosis and other benign anogenital skin conditions.

Codes

ICD10CM:
D04.9 – Carcinoma in situ of skin, unspecified

SNOMEDCT:
402913004 – Bowenoid papulosis

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Bowenoid papulosis is rare in children and would be seen in older, sexually active teenagers.

Best Tests

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Management Pearls

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Therapy

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References

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Last Updated: 04/13/2018
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Bowenoid papulosis - Anogenital in
See also in: Immunocompromised, HIV and AIDS
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View all Images (7)
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Bowenoid papulosis : Labia majora, Penis, Scrotum, Verrucous scaly papule
Clinical image of Bowenoid papulosis
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