Bromoderma
Alerts and Notices
Synopsis
Gastrointestinal (GI) symptoms of bromism include anorexia, weight loss, and nausea. Central nervous system (CNS) manifestations observed are ataxia and tremor along with confusion, delirium, or even full psychosis.
Bromoderma may develop more frequently in patients with renal impairment due to elongation of bromide half-life.
Bromine and bromides can be found in prescription medications (eg, ipratropium bromide) and over-the-counter (OTC) medications (eg, dextromethorphan hydrobromide). Rarely, brominated vegetable oil (BVO) is still used as an emulsifier in citrus-based soft drinks.
Codes
ICD10CM:L27.8 – Dermatitis due to other substances taken internally
SNOMEDCT:
8007005 – Bromoderma
Look For
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Impetigo
- Impetigo, non-bullous (and pyoderma vegetans)
- Ecthyma
- Acne
- Majocchi granuloma
- Sweet syndrome
- Furunculosis
- Sporotrichosis
- Deep fungal infections – blastomycosis, chromoblastomycosis, cryptococcosis
- Botryomycosis
- Fluoroderma
- Iododerma
- Calciphylaxis
- Pyoderma gangrenosum
- Cutaneous T-cell lymphoma – plaque and tumor forms
- Actinomycosis
- Eumycetoma
- Abscess
- Cutaneous tuberculosis and atypical mycobacteria
- Nocardiosis
- Syphilis, tertiary
- Tularemia
Best Tests
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Management Pearls
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Therapy
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Drug Reaction Data
Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.Subscription Required
References
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Last Reviewed:10/27/2021
Last Updated:10/27/2021
Last Updated:10/27/2021
Bromoderma