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Bullous impetigo (pediatric) - Anogenital in
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Bullous impetigo (pediatric) - Anogenital in

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Contributors: Erin X. Wei MD, Molly Plovanich MD, Belinda Tan MD, PhD, Amy Swerdlin MD, Gomathy Sethuraman MD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

This summary discusses pediatric patients. Bullous impetigo in adults is addressed separately. 

Bullous impetigo is a localized form of staphylococcal scalded skin syndrome caused by exfoliative toxins (A and B) released by (phage group II) Staphylococcus aureus. These toxins cleave desmoglein 1, resulting in superficial blisters locally at the site of infection. It is primarily seen in children, especially infants, who lack antibodies against exfoliative toxins, and only rarely occurs in teenagers or young adults. Infection is spread by direct contact with colonized or infected individuals. Staphylococcus aureus often colonizes the nares, umbilicus, nails, and eyes; approximately 5% of S aureus has exfoliative toxin.

Bullous impetigo initially presents as flaccid bullae, which then rupture, leaving round erosions that become crusted. Constitutional symptoms and fever are rare and mild, if they occur. The disease commonly affects the intertriginous areas, face, and extremities.

Outbreaks tend to occur during the summer months and in humid climates. Full resolution typically occurs within 2-6 weeks. Rare progression to staphylococcal scalded skin syndrome can occur.

In neonates, the infection often presents in the first 2 weeks of life. Sometimes, bullous impetigo may result in serious infections like osteomyelitis, septic arthritis, pneumonia, and septicemia.

Codes

ICD10CM:
L01.03 – Bullous impetigo

SNOMEDCT:
399183005 – Impetigo bullosa

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Last Reviewed:03/22/2022
Last Updated:05/05/2022
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Bullous impetigo (pediatric) - Anogenital in
See also in: Overview
A medical illustration showing key findings of Bullous impetigo (pediatric) : Axilla, Face, Flaccid bullae, Grouped configuration, Neck, Scattered few, Inguinal region, Vesicles
Clinical image of Bullous impetigo (pediatric) - imageId=1830777. Click to open in gallery.  caption: 'A large superficial purulent bulla and surrounding erythema on the forearm.'
A large superficial purulent bulla and surrounding erythema on the forearm.
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