Bullous pemphigoid of childhood in Infant/Neonate
Bullous pemphigoid is a chronic autoimmune, subepidermal, vesiculobullous disease that is rarely seen in infants, children, and adolescents (it is most frequently seen in elderly individuals). The disease can occur anywhere, including the oral mucosa. In infants, it may predominate on the palms and soles. In adolescents, it has been reported to resemble adult disease without oral erosions.
On one end of the spectrum, the disease can be severe and generalized, and patients can feel quite ill; on the other end of the spectrum, patients can have a few asymptomatic bullae in localized areas (eg, on the legs). Genital involvement is reported to occur in just under half of cases. Localized bullous pemphigoid of the genital skin is exceedingly rare and is reported in children aged 7-12. Girls are affected more frequently than boys.
In some instances, early bullous pemphigoid lesions will appear as pruritic urticarial papules and plaques.
The condition is often self-limiting, but it can take months to years to resolve.
L12.0 – Bullous pemphigoid
402439006 – Childhood bullous pemphigoid
- Bullous dermatosis of childhood
- Herpes simplex virus (HSV)
- Bullous impetigo
- Epidermolysis bullosa acquisita
- Epidermolysis bullosa simplex
- Mucous membrane pemphigoid
- Linear IgA dermatosis
- Dermatitis herpetiformis
- Bullous fixed drug eruption
- Stevens-Johnson syndrome
- Immunoglobulin A vasculitis (formerly Henoch-Schönlein purpura)
- Child abuse