Carpal tunnel syndrome - Nail and Distal Digit
Mild carpal tunnel syndrome is typically not associated with dermatologic findings. When long-standing, autonomic nerve dysfunction occurs, resulting in necrotic carpal tunnel syndrome. Dermatologic manifestations will then include bullae, ulcers, hypohidrosis, vasospasm, and Raynaud phenomenon. Nail changes may also occur and may be a clue to diagnosis of carpal tunnel syndrome.
Nail changes are more common in women, with a median age of 54 years. The right hand is more often involved than the left.
There are case reports of carpal tunnel-associated nail changes in children and young adults; however, it is very rare in children. For late stage carpal tunnel syndrome presenting in children, genetic or metabolic causes should be explored, although there are reports of sporadic cases. These include lysosomal storage diseases (familial thickening of the transverse ligament and diabetes mellitus). Other reported causes are repetitive wrist motion, median nerve fibrolipomas or hemangiomas, hemophilia, automutilation, and trauma.
G56.00 – Carpal tunnel syndrome, unspecified upper limb
57406009 – Carpal tunnel syndrome
Differential Diagnosis & Pitfalls
Drug Reaction Data