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SynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyDrug Reaction DataReferences
Emergency: requires immediate attention
Cerebral venous thrombosis
Other Resources UpToDate PubMed
Emergency: requires immediate attention

Cerebral venous thrombosis

Contributors: Andrea Wasilewski MD, Richard L. Barbano MD, PhD
Other Resources UpToDate PubMed

Synopsis

Cerebral venous thrombosis (CVT) is the development of a thrombosis resulting in partial or complete occlusion of a cerebral venous sinus or cortical vein. Obstruction of the cerebral venous system results in raised intracranial pressure and decreased cerebral perfusion and blood flow, which may lead to venous infarction. The severity of symptoms varies based on the degree and location of the venous occlusion. The superior sagittal sinus is the most frequently occluded cerebral vein. Patients with CVT classically present with some combination of headache, papilledema, seizures, and focal neurologic deficits (ie, cranial nerve palsies, hemiparesis, visual field deficits, hemisensory loss).

CVT most commonly presents in younger patients (ie, second to fourth decade of life) and is an important cause of stroke in this population. CVT is more prevalent in women than men (3:1). Risk factors for the development of CVT include exposure to estrogen-containing oral contraceptives, hypercoagulable states (genetic or acquired), pregnancy, malignancy, and head trauma.

The diagnosis of CVT is often delayed or missed. Patients have a favorable prognosis with timely diagnosis and treatment with anticoagulation. Delayed diagnosis and management may result in cerebral venous infarction with or without associated hemorrhage, lasting neurologic impairment, or death.

Codes

ICD10CM:
G08 – Intracranial and intraspinal phlebitis and thrombophlebitis
O87.3 – Cerebral venous thrombosis in the puerperium

SNOMEDCT:
95455008 – Thrombosis of cerebral veins

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed:09/28/2021
Last Updated:09/28/2021
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Emergency: requires immediate attention
Cerebral venous thrombosis
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A medical illustration showing key findings of Cerebral venous thrombosis : Seizures, Headache, Papilledema, Visual field defect, Hemiparesis
Copyright © 2022 VisualDx®. All rights reserved.