Typically, cervical cancer is diagnosed in women aged older than 30 years. Peak incidence is in the late 40s. The vast majority of women have no symptoms, and the first sign of an abnormality is noted on routine screening. If symptoms are present, they may include abnormal vaginal discharge, abnormal vaginal bleeding, or postcoital bleeding. Symptoms of advanced disease are typically from mass effect leading to low back or pelvic pain, obstructive renal failure, or leg edema.
C53.9 – Malignant neoplasm of cervix uteri, unspecified
363354003 – Malignant tumor of cervix
Differential Diagnosis & Pitfalls
- Cervical polyp
- Pelvic inflammatory disease / cervicitis – STI testing should be completed; cervical motion tenderness is not typically seen with cervical cancer.
- Condyloma acuminata (genital warts)
- Nabothian cyst – Small yellow / white "pearly"-appearing cysts on the cervix; these are normal and need no intervention.
- Cervical ectropion
- Prolapsing uterine fibroid (leiomyoma) – Fleshy, tan-colored mass, typically mobile; a stalk is often seen in the cervical os.
- Prolapsing uterine polyp – Similar to prolapsed fibroid except more friable.
Drug Reaction Data