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Chlamydophila pneumoniae pneumonia
Other Resources UpToDate PubMed

Chlamydophila pneumoniae pneumonia

Contributors: Neil Mendoza MD, Paritosh Prasad MD
Other Resources UpToDate PubMed

Synopsis

Chlamydophilia pneumoniae (also known as Chlamydia pneumoniae) is an obligate intracellular bacterium that causes pneumonia.

Transmission of this infection is thought to occur through respiratory droplets, and institutional outbreaks have been reported. Serologic studies have revealed that many adolescents and most adults are seropositive.

Many patients infected with this pathogen are likely asymptomatic or minimally symptomatic. In symptomatic patients who present for evaluation, fever, cough, and dyspnea are seen. Cough is often nonproductive and may persist for weeks despite therapy.

Clinically, it is not possible to distinguish pneumonia due to C. pneumoniae from pneumonia due to other respiratory pathogens. Also, it is possible to be infected by more than one pathogen at the same time (eg, with Streptococcus pneumoniae and C. pneumoniae). In these cases, it is difficult to determine if C. pneumoniae is responsible for the patient's symptoms or if the other pathogen is more important.

Associations between C. pneumoniae infection and asthma, atherosclerosis, and other chronic conditions have been reported, but the data are not conclusive.

Related topic: community-acquired pneumonia

Codes

ICD10CM:
J16.0 – Chlamydial pneumonia

SNOMEDCT:
233609002 – Chlamydial pneumonia

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

  • Viral respiratory infections (eg, due to Influenza or Respiratory syncytial virus infection)
  • Other "atypical" pneumonia due to Chlamydia psittaci, Tularemia, Coxiella burnetii, Mycoplasma pneumonia, or Legionellosis
  • Other "typical" bacterial pneumonia (eg, due to Streptococcus pneumoniae pneumonia)
  • Respiratory infections due to other pathogens including Pneumocystis jirovecii pneumonia, fungi (including endemic fungi), Atypical mycobacterial infection, or Pulmonary nocardiosis species – consider especially in immunocompromised patients.
  • Congestive heart failure and other noninfectious causes of pulmonary edema

Best Tests

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Management Pearls

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Therapy

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References

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Last Updated:12/01/2020
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Chlamydophila pneumoniae pneumonia
A medical illustration showing key findings of Chlamydophila pneumoniae pneumonia : Hoarseness, Dyspnea, Pharyngitis, Low grade fever, Dry cough
Imaging Studies image of Chlamydophila pneumoniae pneumonia - imageId=6838276. Click to open in gallery.  caption: '<span>Axial CT image shows extensive right upper lobe consolidation with air bronchograms. There are peripheral nodular ground glass opacities. Patient was positive for Chlamydophila pneumonia.</span>'
Axial CT image shows extensive right upper lobe consolidation with air bronchograms. There are peripheral nodular ground glass opacities. Patient was positive for Chlamydophila pneumonia.
Copyright © 2024 VisualDx®. All rights reserved.