Clear cell acanthoma
Pathogenesis is unknown, but some have proposed that it is a variant of a seborrheic keratosis, while others favor a reactive inflammatory dermatosis.
Clear cell acanthoma occurs equally in both sexes and has a peak incidence in the 50- to 70-year age range.
Lesions tend to develop over the course of several years, but rarely an eruptive form may occur.
D23.70 – Other benign neoplasm of skin of unspecified lower limb, including hip
254670002 – Clear cell acanthoma
Differential Diagnosis & Pitfalls
- Lobular capillary hemangioma (pyogenic granuloma)
- Lichenoid keratosis
- Basal cell carcinoma
- Squamous cell carcinoma
- Bowen disease
- Amelanotic melanoma
- Inflamed seborrheic keratosis
- Traumatized hemangioma