Clinical presentation is variable. Continuous skin contact with cobalt may cause irritation or a rash (see allergic contact dermatitis). Acute ingestion of large amounts of cobalt is rare and not known to cause any severe manifestations; patients may commonly present with nausea and vomiting. Chronic absorption of large amounts of cobalt may lead to serious health complications. Potential clinical manifestations include fatigue, cardiomyopathy, cognitive dysfunction, hearing loss, hypothyroidism, neuropathy, polycythemia, tinnitus, and vision loss.
Individuals acutely exposed to large amounts of cobalt usually recover without any long-term complications. However, individuals who experience cobalt toxicity from long-term exposure may have irreversible health problems.
T56.891A – Toxic effect of other metals, accidental (unintentional), initial encounter
111777006 – Cobalt poisoning
Differential Diagnosis & Pitfalls