ContentsSynopsisCodesDifferential Diagnosis & PitfallsBest TestsDrug Reaction DataReferences
Coronary artery disease
Print
Other Resources UpToDate PubMed

Coronary artery disease

Print Images (1)
Contributors: Christine Osborne MD, Ryan Hoefen MD, PhD
Other Resources UpToDate PubMed

Synopsis

A disease with narrowing or blockage in one or more of the coronary arteries causing reduced or absent blood flow to the vessels supplying the heart. Typically, coronary artery disease (CAD) is secondary to atherosclerosis, a ruptured plaque, or a ruptured thrombus leading to symptoms of ischemia including retrosternal chest pain; chest pain with radiation to the neck, jaw, or left arm; palpitations; nausea or heartburn-like symptoms; hypotension; or even death. Some types of coronary disease are not due to atherosclerosis (dissections, vasospasm, vasculitis), but they are unusual.

Risk factors for development of coronary artery disease include increasing age, postmenopausal status in women, family history of CAD before age 50 in a first-degree relative, hypertension, hyperlipidemia, type 2 diabetes mellitus (T2DM), tobacco use, and obesity. 

There is significant evidence that aspirin is not effective for primary prevention.

Codes

ICD10CM:
I25.10 – Atherosclerotic heart disease of native coronary artery without angina pectoris

SNOMEDCT:
53741008 –  Coronary arteriosclerosis

Differential Diagnosis & Pitfalls

Best Tests

Subscription Required

Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

Subscription Required

References

Subscription Required

Last Updated: 10/30/2018
Copyright © 2019 VisualDx®. All rights reserved.
Coronary artery disease
Print 1 Images
Coronary artery disease : Exertional dyspnea, Dyspnea, Exertional angina
Copyright © 2019 VisualDx®. All rights reserved.