Cutaneous myxoma
Alerts and Notices
Synopsis
Cutaneous myxomas typically present as small (< 1 cm) dermal or subcutaneous nodules located on the head, neck, or trunk. Lesions often present by early adulthood and have a tendency to recur following removal. When associated with CNC, additional notable findings include lentigines, blue nevi, cardiac myxomas, and various endocrine and nonendocrine tumors.
Codes
ICD10CM:D21.9 – Benign neoplasm of connective and other soft tissue, unspecified
SNOMEDCT:
92384009 – Benign neoplasm of skin
Look For
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
Based on histologic findings:- Focal dermal mucinosis
- Myxoid neurofibroma (see Carney complex)
- Myxoid neurothekeoma (dermal nerve sheath fibroma)
- Fibromyxoma (see, eg, superficial acral fibromyxoma)
- Myxoid dermatofibrosarcoma protuberans (DFSP)
- Leiomyoma or leiomyosarcoma
- Spindle cell / pleomorphic lipoma
- Lipoma
- Neurofibroma
- Cutaneous lymphoma
- Desmoid tumor
- Angiofibroma
- Cutaneous fibroadenoma (see, eg, fibroadenoma of breast)
- Cutaneous angiomyolipoma
Best Tests
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Management Pearls
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Therapy
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References
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Last Reviewed:05/02/2021
Last Updated:05/26/2021
Last Updated:05/26/2021