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Drug-induced paronychia
See also in: Nail and Distal Digit
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Drug-induced paronychia

See also in: Nail and Distal Digit
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Contributors: Shari Lipner MD, PhD, Susan Burgin MD, Bertrand Richert MD, Robert Baran MD
Other Resources UpToDate PubMed

Synopsis

Paronychia is inflammation of the nail folds and may be either acute or chronic. Acute paronychia occurs rapidly and is associated with redness, pain, and, in the case of infection, purulent drainage. Chronic paronychia lasts for more than 6 weeks and is associated with erythema, loss of the cuticle, and often nail dystrophy.

Acute paronychia is generally due to infectious etiologies, while chronic paronychia is typically due to irritants. Medications are also responsible for some acute and chronic paronychias and correlate with the introduction of the drug. Reported drug culprits include retinoids, lamivudine, cyclosporine, indinavir, azidothymidine (AZT), cephalexin, sulfonamides, cetuximab, gefitinib, fluorouracil (5FU), methotrexate, vandetanib, capecitabine, doxorubicin, and docetaxel. The paronychia typically resolves once the medication is discontinued.

Codes

ICD10CM:
T50.995A – Adverse effect of other drugs, medicaments and biological substances, initial encounter

SNOMEDCT:
71906005 – Paronychia

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed: 07/21/2017
Last Updated: 07/25/2017
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Drug-induced paronychia
See also in: Nail and Distal Digit
Print 11 Images
View all Images (11)
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Drug-induced paronychia : Nail fold erythema and edema, Nail pain, Periungual fingers
Clinical image of Drug-induced paronychia
Copyright © 2019 VisualDx®. All rights reserved.