Dyshidrotic dermatitis in Adult
Dyshidrotic eczema can be associated with atopic dermatitis, contact irritants and allergens, dermatophyte and bacterial infections, hyperhidrosis, hot weather, high dietary intake of nickel or cobalt, and emotional stress. Administration of intravenous immunoglobulin (IVIG) has been associated with severe dyshidrotic dermatitis. There have also been a few reports of dyshidrotic dermatitis in patients treated with secukinumab.
Some cases spontaneously resolve. Treatment is aimed at symptomatic relief and control of vesiculation.
L30.1 – Dyshidrosis [pompholyx]
201201000 – Podopompholyx
402222007 – Vesicular hand eczema
Differential Diagnosis & Pitfalls
- Allergic contact dermatitis – Distinguishing idiopathic dyshidrotic dermatitis from allergic contact dermatitis can be difficult, although contact dermatitis often involves the dorsum of the hand. An extensive history of environmental exposure should be gathered when a vesicular hand rash is present.
- Palmoplantar pustulosis
- Dermatophyte infection (eg, tinea pedis and/or manuum)
- Herpetic whitlow
- Pustular psoriasis
- Bullous impetigo
- In immunocompromised patients, also consider crusted scabies.
- Epidermolysis bullosa simplex
- Porphyria cutanea tarda
- Hand-foot-and-mouth disease
- An unusual acral form of bullous pemphigoid resembles dyshidrotic eczema.
- Dyshidrotic cutaneous T-cell lymphoma
- Erythema multiforme
Drug Reaction Data