ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferencesView all Images (5)
Eccrine angiomatous hamartoma in Adult
Print
Other Resources UpToDate PubMed

Eccrine angiomatous hamartoma in Adult

Print Images (5)
Contributors: Nayan Lamba BA, Susan Burgin MD, Lowell A. Goldsmith MD, MPH
Other Resources UpToDate PubMed

Synopsis

Eccrine angiomatous hamartoma (EAH) is a rare benign tumor characterized by the proliferation of eccrine and vascular elements in the dermis.

EAH typically presents as a red, violaceous, or brownish nodule or plaque on an extremity. Papules or macules are less frequently seen. The face, neck, and trunk may also be primary sites of involvement. Patients report variable levels of pain. This is thought to occur as a result of small nerves that are seen on electron microscopy in close proximity to the eccrine and vascular structures. Hypertrichosis of the tumor is encountered in most cases. Hyperhidrosis is an additional diagnostic feature that is seen in under half of reported cases.

EAH is classically solitary; however, multiple tumors in a Blaschkoid or segmental distribution have been described. EAH grows proportionately with the affected individual.

Females and males are equally affected.

Codes

ICD10CM:
Q85.8  – Other phakomatoses, not elsewhere classified

SNOMEDCT:
239115005 – Eccrine angiomatous hamartoma

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Vascular malformations:
  • Eccrine nevus – Characterized histopathologically by an increase in eccrine structures but not capillaries. Clinical hallmark is hyperhidrosis in most cases.
  • Tufted angioma
  • Smooth muscle hamartoma – These flesh-colored plaques may have associated hypertrichosis. A "chicken-skin" appearance (pseudo-Darier sign) may be seen with piloerection.
  • Glomus tumor – Painful bluish papules, single or multiple, are encountered, mainly on acral areas of the body.
  • Blue rubber bleb nevus
  • Sudoriparous angioma – Another rare, benign tumor where eccrine glands of normal number are seen lying close to vascular structures in the dermis; these have a larger caliber than those seen in EAH.
Macules:

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Updated: 07/14/2016
Copyright © 2018 VisualDx®. All rights reserved.
Eccrine angiomatous hamartoma in Adult
Print 5 Images
View all Images (5)
(with subscription)
Eccrine angiomatous hamartoma : Hypertrichosis, Smooth nodule, Smooth plaque, Hyperhidrosis
Copyright © 2018 VisualDx®. All rights reserved.