Eosinophilic cellulitis in Adult
Eosinophilic cellulitis presents with sudden onset of single or multiple mildly painful or pruritic, erythematous plaques. The lesions are usually seen on the extremities but may be anywhere on the skin and are typically symmetric or widespread. Uncommonly, fever and arthralgias are present. Spontaneous resolution tends to occur over 4-8 weeks. Recurrences may occur. Familial cases have been reported.
Cases may be associated with insect bites, viral infections, parasite infestations, fungal infections, vaccination, and hypersensitivity reactions. More rarely, leukemia, eosinophilic granulomatosis with polyangiitis, and hypereosinophilic syndrome have been reported.
L98.3 – Eosinophilic cellulitis
238931006 – Eosinophilic cellulitis
- Bacterial cellulitis – It may be difficult clinically to differentiate between bacterial and eosinophilic cellulitis in some cases. In eosinophilic cellulitis, plaques are not usually warm or tender to the touch. A differential count may reveal peripheral eosinophilia in eosinophilic cellulitis and neutrophilia in bacterial cellulitis.
- Contact dermatitis
- Insect bites
- Fixed drug eruption
- Granuloma annulare
- Erythema migrans
- Eosinophilic annular erythema
- Urticarial phase of bullous pemphigoid
- Sweet syndrome
- Eosinophilic dermatosis of hematologic malignancy