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Eosinophilic cellulitis in Child
See also in: Cellulitis DDx
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Other Resources UpToDate PubMed

Eosinophilic cellulitis in Child

See also in: Cellulitis DDx
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Contributors: Susan Burgin MD, Art Papier MD
Other Resources UpToDate PubMed

Synopsis

Eosinophilic cellulitis, or Wells syndrome, is a rare disorder of unknown etiology. Eosinophilic cellulitis is reported infrequently in children and is manifested by eosinophil infiltration in the dermis.

Eosinophilic cellulitis presents with sudden onset of single or multiple mildly painful or pruritic, erythematous plaques. The lesions are usually seen on the extremities but may be anywhere on the skin and are typically symmetric or widespread. Uncommonly, fever and arthralgias are present. Spontaneous resolution tends to occur over 4-8 weeks. Recurrences may occur. Familial cases have been reported.

Cases may be associated with insect bites, viral infections, parasite infestations, fungal infections, vaccination, and hypersensitivity reactions. More rarely, leukemia, eosinophilic granulomatosis with polyangiitis, and hypereosinophilic syndrome have been reported.

Codes

ICD10CM:
L98.3 – Eosinophilic cellulitis

SNOMEDCT:
238931006 – Eosinophilic cellulitis

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed: 04/12/2018
Last Updated: 05/07/2019
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Eosinophilic cellulitis in Child
See also in: Cellulitis DDx
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Eosinophilic cellulitis : Erythema, Painful skin lesions, Reticular - netlike, Symmetric extremities, Widespread, Hardened skin, EOS increased
Clinical image of Eosinophilic cellulitis
A large, vesiculated, edematous pink plaque on the arm.
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