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Epidermoid cyst - Anogenital in
See also in: Overview,Hair and Scalp
Other Resources UpToDate PubMed

Epidermoid cyst - Anogenital in

See also in: Overview,Hair and Scalp
Contributors: Susan Burgin MD, Belinda Tan MD, PhD, Lowell A. Goldsmith MD, MPH
Other Resources UpToDate PubMed

Synopsis

Epidermoid cysts or epidermal inclusion cysts are also known as sebaceous cysts, which is a misnomer. These asymptomatic, semi-solid cysts are filled with keratin. The cysts are lined by keratinizing epithelium that is responsible for the soft, "cheesy" keratin contents.

These cysts are common on the scrotum but are rarely found on the penis. The cysts can be located almost anywhere, and besides the scrotum, common places include the face, neck, scalp, or trunk.

The pathogenesis of genital epidermoid cysts is unknown. It is hypothesized that some epidermoid cysts may originate from median raphe cysts.

Codes

ICD10CM:
L72.0 – Epidermal cyst

SNOMEDCT:
419893006 – Epidermoid cyst

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

The presence of multiple epidermoid cysts, and a family history of the same, should lead to the consideration of Gardner syndrome, a heritable disorder associated with gastrointestinal malignancy.
  • Median raphe cyst of penis (calcified epidermoid cyst)
  • Scrotal calcinosis
  • Glomangiomas
  • Neurilemmoma
  • Lipoma
  • Pilar cyst usually has a more firm consistency on palpation.
  • Hidradenitis suppurativa

Best Tests

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Management Pearls

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Therapy

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References

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Last Reviewed:05/08/2017
Last Updated:06/12/2017
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Epidermoid cyst - Anogenital in
See also in: Overview,Hair and Scalp
A medical illustration showing key findings of Epidermoid cyst : Cyst, Face, Neck, Scalp, Smooth nodule, Trunk
Clinical image of Epidermoid cyst - imageId=3463753. Click to open in gallery.  caption: 'A close-up of a yellowish nodule with a central keratin-filled punctum.'
A close-up of a yellowish nodule with a central keratin-filled punctum.
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