Epidural intracranial hematoma
Alerts and Notices
Synopsis

The classic presentation involves a brief post-traumatic loss of consciousness, then several minutes to hours of a lucid interval, followed by obtundation and focal neurologic deficits. While this classic clinical description is widely taught, it is seen in < 20% of cases. Other less specific signs and symptoms include headache, nausea and emesis, seizures, neurologic deficits (contralateral weakness, hyperreflexia), papilledema, pupil-involving third-nerve palsy, somnolence, or coma.
Codes
ICD10CM:S06.4X0A – Epidural hemorrhage without loss of consciousness, initial encounter
S06.4X0S – Epidural hemorrhage without loss of consciousness, sequela
S06.4X9A – Epidural hemorrhage with loss of consciousness of unspecified duration, initial encounter
SNOMEDCT:
428268007 – Extradural intracranial hematoma
Look For
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Subdural hematoma
- Diffuse axonal injury
- Intracerebral hemorrhage
- Subarachnoid hemorrhage
- Concussion
- Postictal state
- Metabolic, infectious, or pharmacologic etiology for altered mental status
- Kernohan notch phenomenon (contralateral cerebral peduncle compressed against tentorial notch) may lead to falsely localizing, ipsilateral neurologic deficits.
- Do not fail to recognize other radiographically visible intracranial injuries, including contrecoup intracranial injuries.
- It is important to evaluate for additional traumatic injuries, especially cervical spine injury.
Best Tests
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Management Pearls
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Therapy
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Drug Reaction Data
Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.Subscription Required
References
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Last Reviewed:08/22/2017
Last Updated:10/30/2019
Last Updated:10/30/2019