The skin lesions usually resolve within 6 months with appropriate treatment.
E78.2 – Mixed hyperlipidemia
238952003 – Eruptive xanthoma
Differential Diagnosis & Pitfalls
- Granuloma annulare – Skin-colored to reddish-brown papules, often forming annular plaques.
- Xanthoma disseminatum should be considered in children; presents with brown to yellow papillary rash on flexor surfaces and often on the eyelids.
- Folliculitis – Follicularly based erythematous papules and pustules.
- Pityrosporum folliculitis – Folliculocentric and often pruritic.
- Steroid acne – Predilection for chest and back, often 2-5 weeks after starting oral steroids.
- Sarcoidosis – May also affect extensor extremities but typically red-brown in color.
- Leukemia cutis – Firm, deep red-brown / plum colored.
- Langerhans cell histiocytosis – Predilection for skin folds.
- Multicentric reticulohistiocytosis – Distribution typically along acral areas (head, hands [especially periungual], and juxta-articular regions of extremities).
- Lichen amyloidosis – Often with rippled appearance.
- Erythema elevatum diutinum – Nodules and plaques over extensor extremities.
Drug Reaction Data